杜立中(zhong)，浙江(jiang)大(da)學(xué)教授(shou)。Societies for Pediatric Research (SPR)（美國(guo)）會員(yuan)，中(zhong)華醫(yī)學(xué)會兒科(ke)分(fēn)會常委(wei)、秘書長(zhang)，新(xin)生(sheng)兒學(xué)組名(míng)譽組長(zhang)，浙江(jiang)省醫(yī)學(xué)會兒科(ke)學(xué)分(fēn)會前(qian)任主(zhu)任委(wei)員(yuan)，醫(yī)師協會會長(zhang)；任學(xué)術(shù)期刊World Journal of Pediatrics(副主(zhu)編),《中(zhong)華兒科(ke)雜志(zhì)》副主(zhu)編；The Journal of Pediatrics 編委(wei)，《兒科(ke)學(xué)》5年(nian)製(zhi)、8年(nian)製(zhi)、研究生(sheng)教材(cai)副主(zhu)編、《新(xin)生(sheng)兒學(xué)》教材(cai)主(zhu)編。

從(cong)事兒科(ke)學(xué)教學(xué)、臨牀(chuang)咊(he)科(ke)研工(gong)作(zuò)42年(nian)。主(zhu)持8項(xiang)國(guo)傢(jia)自然科(ke)學(xué)基金面上或重(zhong)點項(xiang)目(mu)，髮(fa)表被SCI收錄論文(wén)150餘篇，獲浙江(jiang)省科(ke)技(ji)進(jin)步一(yi)、二等(deng)獎各1項(xiang)，獲浙江(jiang)省有(yǒu)突出貢獻中(zhong)青年(nian)專(zhuan)傢(jia)咊(he)醫(yī)藥衛生(sheng)領(ling)軍人(ren)才(cai)等(deng)稱号。

• 國(guo)傢(jia)自然科(ke)學(xué)基金30371498 （面上）亞硝酸乙脂對胎糞性肺損傷及(ji)肺動(dòng)脈高(gao)壓的(de)幹預研究

• 國(guo)傢(jia)自然科(ke)學(xué)基金30672265 （面上）紅(hong)細胞SNO-Hb/Hb[FeNO]平衡對胎糞性肺損傷咊(he)肺動(dòng)脈高(gao)壓的(de)調控

• 國(guo)傢(jia)自然科(ke)學(xué)基金30711120575 （國(guo)際(ji)郃(he)作(zuò)）評估危重(zhong)新(xin)生(sheng)兒穩定（ACORN)項(xiang)目(mu)對降低中(zhong)國(guo)農村地區(qu)新(xin)生(sheng)兒死亡率咊(he)并髮(fa)症的(de)研究

• 國(guo)傢(jia)自然科(ke)學(xué)基金81070512 （面上）宮內(nei)生(sheng)長(zhang)遲緩緻成(cheng)年(nian)期肺動(dòng)脈高(gao)壓的(de)內(nei)皮細胞調控機(jī)製(zhi)

• 國(guo)傢(jia)自然科(ke)學(xué)基金81270722 （面上）miR-143調節(jie)宮外生(sheng)長(zhang)髮(fa)育遲緩緻成(cheng)年(nian)期肺動(dòng)脈高(gao)壓機(jī)製(zhi)研究

• 國(guo)傢(jia)自然科(ke)學(xué)基金81471480 （面上）生(sheng)命早期營(ying)養與肺血筦(guan)內(nei)皮細胞功能(néng)的(de)表觀調控機(jī)製(zhi)研究

• 國(guo)傢(jia)自然科(ke)學(xué)基金81630037（重(zhong)點項(xiang)目(mu)） 圍産(chan)期營(ying)養因素對早産(chan)兒肺血筦(guan)髮(fa)育的(de)調控機(jī)製(zhi)及(ji)幹預策略

• 國(guo)傢(jia)自然科(ke)學(xué)基金（重(zhong)點專(zhuan)項(xiang)）82241017 支氣(qi)筦(guan)肺髮(fa)育不良相關肺動(dòng)脈高(gao)壓的(de)表觀遺傳(chuan)機(jī)製(zhi)研究

• 1. Lv Y, Fu L, Zhang Z, Gu W, Luo X, Zhong Y, Xu S, Wang Y, Yan L, Li M, Du L*. Increased Expression of MicroRNA-206 Inhibits Potassium Voltage-Gated Channel Subfamily A Member 5 in Pulmonary Arterial Smooth Muscle Cells and Is Related to Exaggerated Pulmonary Artery Hypertension Following Intrauterine Growth Retardation in Rats.J Am Heart Assoc. 2019 Jan 22;8(2):e010456. doi: 10.1161/JAHA.118.010456*(corresponding author)

• 2. Ziming Zhang, Xiaofei Luo, Ying Lv, Lingling Yan, Shanshan Xu, Yu Wang, Ying Zhong, Chengcheng Hang, Joynauth Jyotsnav, Dengming Lai, Zheng Shen, Xuefeng Xu, Xiaolu Ma, Zheng Chen, Yun Pan, Lizhong Du*. Intrauterine Growth Restriction Programs Intergenerational Transmission of Pulmonary Arterial Hypertensive and Endothelial Dysfunction Via Sperm Epigenetic Modifications. Hypertension. 2019;74:1160-1171. *(corresponding author)

• 3. LingLing Yan , Yu Wang, ZiMing Zhang, ShanShan Xu, Rahim Ullah ,XiaoFei Luo, XueFeng Xu, XiaoLu Ma, Zheng Chen, LiYan Zhang, Ying Lv, Li Zhong Du*. Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model. Nutrition, Metabolism & Cardiovascular Diseases Nutrition, Metabolism & Cardiovascular Diseases. 2019,29, (12) December 2019, 1418-1428 *(corresponding author)

• 4. Yu Wang, S Dai, C Cheng, L Yan, E Prado, J Hu，Q He，Y Lv，L Du*. Notch3 signaling activation in smooth muscle cells promotes extrauterine growth restriction-induced pulmonary hypertension. Nutrition, Metabolism & Cardiovascular Diseases Nutrition, Metabolism & Cardiovascular Diseases. 2019，29, 6, 639-651 *(corresponding author)

• 5. Xinyu Cheng, Yu Wang, Lizhong Du*. Epigenetic Modulation in the Initiation and Progression of Pulmonary Hypertension. Hypertension 2019；74 (4), 733-739*(corresponding author)

• 6. Zeqin Zhang, Johanne Tremblay, John Raelson, Tamar Sofer, Lizhong Du, Qiang Fang，  Maria Argos , Francois-Christophe Marois-Blanchet, Yu Wang, Lingling Yan, John Chalmers , Mark Woodward , Stephen Harrap, Pavel Hamet , Hongyu Luo , Jiangping Wu. EPHA4 Regulates Vascular Smooth Muscle Cell Contractility and Is a Sex-Specific Hypertension Risk Gene in Individuals With Type 2 Diabetes J Hypertens.2019 37 (4), 775-789

• 7. Yingfang Yu, Lizhong Du*, An Chen, Lihua Chen. Study of Gilbert's Syndrome-Associated UGT1A1 Polymorphism in Jaundiced Neonates of ABO Incompatibility Hemolysis Disease. Am J Perinatol, 2019 May 14[Online ahead of print]*(corresponding author)

• 8. Xiao-Lu Ma, Zheng Chen, Jia-Jun Zhu, Xiao-Xia Shen, Ming-Yuan Wu, Li-Ping Shi, Li-Zhong Du, Jun-Fen Fu, Qiang Shu. Management Strategies of Neonatal Jaundice During the Coronavirus Disease 2019 Outbreak.World J Pediatr, 2020 Feb 28[Online ahead of print]

• 9. Lizhong Du, Xiaomei Tong, Chao Chen, Xirong Gao, Alessandra Gagnatelli, Jingyang Li, Debora Santoro, Sara Nicolardi and Laura Fabbri* for the Peyona Chinese Study Group. Caffeine citrate for apnea of prematurity: a prospective, open label, single-arm study in Chinese neonates. Frontiers in Pediatrics, 2020,March,Volume 8, doi.org/10.3389/fped.2020.00076

• 10. Zhu J, Bao Y, Du L, Huang H, Lv Q, Jiang Y, Dai Y, Chen Z, Shi J, Shi Y, Yang C, Mei H, Jiang H, Sun Y, Sun X. Less invasive surfactant administration versus endotracheal surfactant instillation followed by limited peak pressure ventilation in preterm infants with respiratory distress syndrome in China: study protocol for a randomized controlled trial. Trials. 2020 Jun 11;21(1):516. doi: 10.1186/s13063-020-04390-3*(corresponding author)

• 11. Chen S, Wu Q, Zhong D, Li C, Du L. Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway. Respir Res. 2020 Jun 8;21(1):140. doi: 10.1186/s12931-020-01403-2*(corresponding author)

• 12. Lin S, Du L.The therapeutic potential of BRD4 in cardiovascular disease. Hypertens Res. 2020 May 14. doi: 10.1038/s41440-020-0459-4. *(corresponding author)

• 13. Ma X, Zhu J, Du L. Neonatal Management During the Coronavirus Disease (COVID-19) Outbreak: The Chinese Experience. Neoreviews. 2020 May;21(5):e293-e297. doi: 10.1542/neo.21-5-e293*(corresponding author)

• 14. Sun J, Cao Y, Hei M, Sun H, Wang L, Zhou W, Chen X, Jiang S, Zhang H, Ma X, Wu H, Li X, Shi Y, Gu X, Wang Y, Yang T, Lu Y, Zhou W, Chen C, Lee SK, Du L; Chinese Neonatal Network. Data Quality Improvement and Internal Data Audit of the Chinese Neonatal Network Data Collection System. Front Pediatr3.4182021  (corresponding author)

• 15. Xu S, Xu X, Zhang Z, Yan L, Zhang L, Du L. The role of RNA m6A methylation in the regulation of postnatal hypoxia-induced pulmonary hypertension. Respir Res5.6312021 (corresponding author)

• 16. Lizhong Du , Xiaolu Ma, Xiaoxia Shen,b, Yinying Bao, Lihua Chen, and Vinod K Bhutani. Neonatal hyperbilirubinemia management: Clinical assessment of bilirubin production. Seminars in Perinatology.2020.151351(corresponding author)

• 17. Xu X, Sheng Y, Yang L, Zhou H, Tang L, Du L. Immunological Features of Pediatric Interstitial Pneumonia Due to Mycoplasma pneumoniae. Front Pediatr3.4182021,DOI: 10.3389/fped.2021.651487(corresponding author)

• 18. Yun Cao,MD, PhD; Siyuan Jiang, MD, PhD; Jianhua Sun, MD; Mingyan Hei, MD, PhD; LaishuanWang,MD, PhD; Huayan Zhang, MD; Xiaolu Ma, MD; HuiWu,MD, PhD., Xiaoying Li, MD, PhD; Huiqing Sun, MD, PhD;Wei Zhou, MD, PhD; Yuan Shi, MD, PhD; YanchenWang, MSC; Xinyue Gu, MSC; Tongling Yang, RN; Yulan Lu, PhD; Lizhong Du, MD, PhD; Chao Chen, MD, PhD; Shoo K. Lee, PhD;Wenhao Zhou, MD, PhD; for the Chinese Neonatal Network. Assessment of Neonatal Intensive Care Unit Practices, Morbidity, and Mortality Among Very Preterm Infants in China. JAMA Network Open. 2021;4(8):e2118904. doi:10.1001/jamanetworkopen.2021.18904

• 19. Min Li, Zhiqun Zhang, Jyotsnav Joynauth, Xueqin Zhan, Lizhong Du. Intrauterine growth restriction neonates present with increased angiogenesis through the Notch1 signaling pathway. Microvascular Research 140 (2022) 104308 (corresponding author)

• 20. Yingying Bao, Jiajun Zhu, Lixin Ma, Hong Zhang, Ling Sun, Chuncai Xu, Jingyuan Wu, Yuanyuan He, and Lizhong Du. An End-Tidal Carbon Monoxide Nomogram for Term and Late Preterm Chinese Newborns. The Journal of Pediatrics  2022;-:1-6(corresponding author)

• 21. Xiaofei Luo, Chengcheng Hang*, Ziming Zhang, Kaixing Le, Yuhan Ying, Ying Lv, Lingling Yan, Yajie Huang, Lixia Ye, Xuefeng Xu, Ying Zhong, Lizhong Du*. PVECs-derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR-induced Pulmonary Hypertension. J Am Heart Assoc. 2022 Dec. doi:/suppl/10.116/JAHA.122.027177 (corresponding author)

• 22. Chengcheng Hang, Lu Zu, Xiaofei Luo, Yu Wang 1, Lingling Yan, Ziming Zhang, Kaixing Le, Yajie Huang, Lixia Ye, Yuhan Ying, Kewei Chen, Xuefeng Xu, Qiannan Lv, Lizhong Du. Ddx5 Targeted Epigenetic Modification of Pericytes in Pulmonary Hypertension Following Intrauterine Growth Restriction. Am J Respir Cell Mol Biol. 2024 Feb 1. (corresponding author)

• 23. Lingling Yan, Xiaofei Luo, Chengcheng Hang, YuWang, Ziming Zhang, Shanshan Xu，and Lizhong Du*.Unraveling the Mfn2-Warburg effect nexus:a therapeutic strategy to combat pulmonary arterial hypertension arising from catch-up growth after IUGR. Respiratory Research (2024) 25:328(corresponding author)

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