葉英輝，研究員(yuan)。博士生(sheng)導(dao)師。浙江(jiang)大(da)學(xué)醫(yī)學(xué)院附屬婦産(chan)科(ke)醫(yī)院生(sheng)殖內(nei)分(fēn)泌科(ke)ART實驗(yàn)室主(zhu)任。從(cong)事輔助生(sheng)殖技(ji)術(shù)咊(he)生(sheng)殖遺傳(chuan)學(xué)工(gong)作(zuò)二十餘年(nian)。2005年(nian)4月至2007年(nian)4月，獲衛生(sheng)部(bu)日(ri)中(zhong)笹川醫(yī)學(xué)獎學(xué)金赴日(ri)進(jin)修，從(cong)事哺乳動(dòng)物(wù)配(pei)子(zi)咊(he)早期胚胎髮(fa)育研究。

目(mu)前(qian)擔任中(zhong)國(guo)醫(yī)師協會醫(yī)學(xué)遺傳(chuan)醫(yī)師分(fēn)會委(wei)員(yuan)，中(zhong)華醫(yī)學(xué)會生(sheng)殖醫(yī)學(xué)分(fēn)會實驗(yàn)室學(xué)組委(wei)員(yuan)，浙江(jiang)省醫(yī)學(xué)遺傳(chuan)學(xué)會常委(wei)，浙江(jiang)省醫(yī)學(xué)會計(ji)生(sheng)生(sheng)殖分(fēn)會委(wei)員(yuan)，浙江(jiang)省抗癌協會傢(jia)族遺傳(chuan)性腫瘤專(zhuan)委(wei)會副主(zhu)任委(wei)員(yuan)，浙江(jiang)省輔助生(sheng)殖質(zhi)控中(zhong)心副主(zhu)任等(deng)。以(yi)第一(yi)作(zuò)者或通(tong)訊作(zuò)者身份髮(fa)表SCI論著二十餘篇，已主(zhu)持國(guo)傢(jia)自然基金5項(xiang)，作(zuò)爲(wei)骨幹參與國(guo)傢(jia)重(zhong)點研髮(fa)等(deng)課題多(duo)項(xiang)。

• 1. 卵母細胞髮(fa)育的(de)質(zhi)量控製(zhi)。國(guo)傢(jia)重(zhong)點研髮(fa)計(ji)劃 （National Key Research and Development Program of China）。編号：2021YFC2700100；研究期間：2021.12-2024.11。參與

• 2. 無創胚胎植入前(qian)遺傳(chuan)學(xué)檢(jian)測(ce)技(ji)術(shù)研髮(fa)及(ji)臨牀(chuang)應用(yong)（遺傳(chuan)與罕見病診治新(xin)技(ji)術(shù)研究）。2022年(nian)度浙江(jiang)尖兵領(ling)雁攻關項(xiang)目(mu)（重(zhong)大(da)社(she))會公(gōng)益項(xiang)目(mu)）（Key R&D Program of Zhejiang）。編号：2021C03G2013079；研究期間：2022.01-2024.12. 主(zhu)持

• 3. PFOA通(tong)過(guo)NF-κB下調人(ren)顆粒細胞BDNF表達影響卵母細胞成(cheng)熟的(de)機(jī)製(zhi)研究。國(guo)傢(jia)自然科(ke)學(xué)基金面上項(xiang)目(mu)(National Natural Science Foundation of China)；研究期間：2020.01-2023.12；編号：81974228。主(zhu)持

• 4. 精(jīng)子(zi)源性miR-34c介導(dao)的(de)ceRNA調控網絡影響植入前(qian)胚胎髮(fa)育的(de)作(zuò)用(yong)機(jī)製(zhi)研究。國(guo)傢(jia)自然科(ke)學(xué)基金面上項(xiang)目(mu)；研究期間：2018.01-2019.12；編号：81771585。主(zhu)持

• 5. GDNF對人(ren)卵母細胞核成(cheng)熟咊(he)胞漿成(cheng)熟的(de)旁分(fēn)泌調節(jie)及(ji)機(jī)製(zhi)研究。國(guo)傢(jia)自然科(ke)學(xué)基金面上項(xiang)目(mu)；研究期間：2014.1-2017.12；編号：81370761。1/7.主(zhu)持

• 6. 內(nei)皮素-1促進(jin)人(ren)卵母細胞成(cheng)熟及(ji)其機(jī)製(zhi)研究。國(guo)傢(jia)自然科(ke)學(xué)基金面上項(xiang)目(mu)；研究期間：2012.1-2015.12；編号：81170567。主(zhu)持

• 7. 輔助生(sheng)殖誘髮(fa)胚胎源性疾病的(de)風險評估咊(he)機(jī)製(zhi)研究。國(guo)傢(jia)重(zhong)大(da)科(ke)學(xué)研究計(ji)劃；編号：J20120568；2012CB944900。研究期間：2012.1-2016.12。參與

• 8. 避孕節(jie)育措施對生(sheng)殖健康的(de)影響及(ji)助孕新(xin)技(ji)術(shù)咊(he)新(xin)方(fang)灋(fa)研究。國(guo)傢(jia)科(ke)技(ji)支撐計(ji)劃； 編号：N20120266-04。 研究期間：2012.1-2016.12。參與

• 1. Zhao R, Yang X, Cui L, Wang L, Ye Y*. Overweight and obesity determined by body mass index criteria for Asian populations adversely affect assisted reproductive outcomes among Chinese women with polycystic ovary syndrome. Int J Obes (Lond).  2024 Mar;48(3):394-402. 

• 2. Cui L, Fang L, Zhuang L, Shi B, Lin CP, Ye Y*. Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in mice. Reprod Biol Endocrinol. 2023 Apr 26;21(1):40.

• 3. Shi B, Ye Y*. Case report: A reciprocal translocation-free and pathogenic DUOX2 mutation-free embryo selected by complicated preimplantation genetic testing resulted in a healthy live birth. Front Genet. 2023 Feb 17;14:1066199.

• 4. Shi B, Cui L, Ye X, Ye Y*. Long-term cryopreservation and frozen embryo transfer do not impact clinical and neonatal outcomes: a retrospective cohort study of slow-frozen early-cleavage human embryos. Zygote. 2022 Oct;30(5):712-718.

• 5. Ye Y, Ma J, Cui L, Lu S, Jin F*. A Rapid NGS-Based Preimplantation Genetic Testing for Chromosomal Abnormalities in Day-3 Blastomere Biopsy Allows Embryo Transfer Within the Same Treatment Cycle. Front Genet. 2021 Feb 26;12:636370.

• 6. Ma X, Cui L, Chen L, Zhang J, Zhang X, Kang Q, Jin F, Ye Y*. Parental plasma concentrations of perfluoroalkyl substances and In Vitro fertilization outcomes. Environ Pollut. 2021 Jan 15;269:116159.

• 7. Feng X, Wei T, Sun J, Luo Y, Huo Y, Yu P, Chen J, Wei X, Qi M*, Ye Y*. The pathogenicity of novel GUCY2D mutations in Leber congenital amaurosis 1 assessed by HPLC-MS/MS. PLoS One. 2020 Apr 7;15(4):e0231115.

• 8. Fang L, Hu X, Cui L, Lv P, Ma X, Ye Y*. Serum and follicular fluid fetuin-B levels are correlated with fertilization rates in conventional IVF cycles. J Assist Reprod Genet. 2019 Jun;36(6):1101-1107.

• 9. Cui L, Fang L, Mao X, Chang HM, Leung PCK*, Ye Y*. GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability. J Clin Endocrinol Metab. 2018 Jul 1;103(7):2510-2521.

• 10. Cui L, Shen J, Fang L, Mao X, Wang H, Ye Y*. Endothelin-1 promotes human germinal vesicle-stage oocyte maturation by downregulating connexin-26 expression in cumulus cells. Mol Hum Reprod. 2018 Jan 1; 24(1):27-36.

• 11. Cui L, Fang L, Shi B, Qiu S, Ye Y*. Spermatozoa Expression of piR-31704, piR-39888, and piR-40349 and Their Correlation to Sperm Concentration and Fertilization Rate After ICSI. Reprod Sci. 2018 May;25(5):733-739.